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How does embryo transfer work?

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Embryo transfer is a critical step in IVF success, requiring close coordination between the fertility specialist and the embryologist.

Timing of the Transfer

  • Usually performed between Day 2 and Day 5 after egg retrieval for a fresh embryo transfer.
  • The exact day depends on embryo development and clinic protocol.

The Procedure

1. Preparation

  • The woman is positioned in a gynecological exam chair.
  • A speculum is inserted to expose the cervix.
  • The cervix is gently cleaned, and any excess cervical mucus is removed.

2. Embryo Transfer Process

  • A trial transfer may be done first with an empty catheter to ensure smooth entry into the uterus. Some clinics perform this test in a prior consultation or on egg retrieval day.
  • The selected embryo(s) are placed in a thin catheter attached to a syringe.
  • Under ultrasound guidance, the catheter is carefully inserted through the cervical canal into the uterine cavity.
  • The embryo(s) are deposited 1 to 1.5 cm from the top of the uterus, optimizing implantation potential.

3. Post-Transfer Check

  • The catheter is removed and checked by the embryologist to ensure no embryo remains inside.
  • If an embryo stays in the catheter, the procedure is repeated immediately with no impact on success rates.

Optimizing the Procedure

  • A semi-full bladder is recommended, as it gently shifts the uterus into a better position for catheter insertion.
  • The procedure is painless for most women and does not require anesthesia, though some women with cervical sensitivity may experience mild discomfort.
  • If local or general anesthesia is used, it does not reduce pregnancy success rates.
  • Embryo transfer is a quick, delicate, and precise procedure, maximizing the chances of implantation.

General information, not a diagnosis: talk to your doctor about your own situation.

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Written by

  • Prof. Arash Rafii

    Professor of Obstetrics, Gynecology and Genetic Medicine

    Sidra Hospital

  • Prof. Michaël Grynberg

    Professor of Reproductive Medicine, Obstetrics and Gynecology

    Antoine Béclère and Jean Verdier University Hospitals

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