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How is endometriosis managed?

1 min read

The main goals of endometriosis treatment are to reduce symptoms, slow the progression of lesions, and support fertility in women who wish to conceive. Management options include medical treatments and surgical interventions, depending on the severity of symptoms and individual goals.

What Are the Medical Treatments for Endometriosis?

Medical treatments focus on reducing estrogen production, as this hormone fuels the growth of endometriosis lesions. Many treatments work by suppressing menstruation, which helps prevent the retrograde flow of endometrial tissue and may slow disease progression. Commonly used options include:

  • Continuous combined oral contraceptives (estrogen-progestin pills)
  • Progestins (such as dienogest or norethisterone)
  • GnRH analogs, which create a temporary menopause-like state
  • Danazol, a synthetic androgen that lowers estrogen levels

These medications can reduce symptoms in 45-65% of cases, but symptoms often return once treatment is stopped. Because of this, many women use long-term management strategies tailored to their specific needs.

What Is the Role of Surgery in Endometriosis?

Surgery is an option when medical treatments are insufficient, when pain is severe, or when fertility is affected. The goal of surgery is to restore normal anatomy by removing adhesions and lesions, which can help relieve pain and improve fertility outcomes.

Most procedures are performed via laparoscopy, a minimally invasive technique. During surgery, superficial lesions can be burned or excised, endometriotic cysts may be drained, and in more severe cases, deep lesions might require removal from the intestines, bladder, or other organs. In complex cases, multidisciplinary surgical teams may be involved to ensure optimal outcomes.

Learn. Improve. Maintain.

Endometriosis is a complex condition that requires a personalized approach. Learning about treatment options, improving symptom management through a combination of medical and lifestyle strategies, and maintaining long-term follow-up with a specialist can help women regain control over their health and well-being.

General information, not a diagnosis: talk to your doctor about your own situation.

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Written by

  • Prof. Arash Rafii

    Professor of Obstetrics, Gynecology and Genetic Medicine

    Sidra Hospital

  • Prof. Michaël Grynberg

    Professor of Reproductive Medicine, Obstetrics and Gynecology

    Antoine Béclère and Jean Verdier University Hospitals

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