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Can we reverse the impact of age on fertility?

1 min read

The biological mechanisms behind age-related infertility are well understood, but current medical treatments cannot fully reverse ovarian aging. As a result, when assisted reproductive technologies (ART) fail—or sometimes even before attempting them—couples may be advised to explore alternative paths such as egg donation or adoption.

Egg donation is one of the most effective solutions for overcoming poor egg quality due to age. In this process, a younger woman (typically under 30) donates her eggs, which are then fertilized with the partner’s sperm to create embryos with higher implantation potential. This significantly improves success rates, with pregnancy rates from egg donation reaching 60-70%, confirming that egg quality—not the uterus—is the primary limiting factor in age-related infertility.

Learn. Improve. Maintain.

While ovarian aging cannot be reversed, understanding fertility options empowers women to make informed decisions. Learning about reproductive aging, improving fertility planning with expert guidance, and maintaining realistic expectations can help navigate this journey with clarity and confidence.

General information, not a diagnosis: talk to your doctor about your own situation.

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Written by

  • Prof. Arash Rafii

    Professor of Obstetrics, Gynecology and Genetic Medicine

    Sidra Hospital

  • Prof. Michaël Grynberg

    Professor of Reproductive Medicine, Obstetrics and Gynecology

    Antoine Béclère and Jean Verdier University Hospitals

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